Adding some certain compound to certain chemical reactions, such as: 2058-72-2, name is 5-Bromo-1-methylindoline-2,3-dione, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2058-72-2. 2058-72-2
General procedure: A mixture of isatin (1.0 mmol), alpha-amino acid (1.0 mmol) and aroylacrylic acid (1.0 mmol) in 4.0 mL aqueous methanol(1:3) was heated in an oil bath to reflux temperature for about 20 min or stirred at room temperature from 25 min to 12 hours. The resulting precipitates were collected by filtration and washed with cold methanol to give analytically pure products 6.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 5-Bromo-1-methylindoline-2,3-dione.
Reference:
Article; Pavlovskaya, Tatyana L.; Yaremenko, Fedor G.; Lipson, Victoria V.; Shishkina, Svetlana V.; Shishkin, Oleg V.; Musatov, Vladimir I.; Karpenko, Alexander S.; Beilstein Journal of Organic Chemistry; vol. 10; (2014); p. 117 – 126;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem