Adding some certain compound to certain chemical reactions, such as: 15362-40-0, name is 1-(2,6-Dichlorophenyl)-2-indolinone, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 15362-40-0. 15362-40-0
General procedure: Compounds 4-9 were prepared through knoevenagel condensation of compounds 12 and 13 (1 mmol) with active methylene compounds including 1-(3-chlorophenyl)-3-methyl-2-pyrazolin-5-one, oxindole and indolinone (1 mmol). The reactants were heated at 160-180 C for about 10-20 min in oil bath and the completion of the reaction was monitored using TLC. The crude products were solidified by triturating with diethyl ether and purified by recrystallization and column chromatography.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1-(2,6-Dichlorophenyl)-2-indolinone.
Reference:
Article; Singh, Palwinder; Shaveta; Sharma, Surbhi; Bhatti, Rajbir; Bioorganic and Medicinal Chemistry Letters; vol. 24; 1; (2014); p. 77 – 82;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem