Continuously updated synthesis method about 104618-32-8

Statistics shows that 2-(4-Oxocyclohexyl)isoindoline-1,3-dione is playing an increasingly important role. we look forward to future research findings about 104618-32-8.

104618-32-8, Name is 2-(4-Oxocyclohexyl)isoindoline-1,3-dione, 104618-32-8, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows.

EXAMPLE 3 3-Amino-6-methoxy-1,2,3,4-tetrahydrocarbazole hydrochloride Reaction of 4-methoxyphenyl hydrazine hydrochloride (0.87 g, 5.0 mmol) with 4-phthalimido-cyclohexanone (1.22 g, 5.0 mmol) in ethanol (20 ml) heated under reflux for 2 hr, followed by cooling and removal of the precipitated solid by filtration gave 3-phthalimido-6-methoxy-1,2,3,4-tetrahydrocarbazole (1.62 g).

Statistics shows that 2-(4-Oxocyclohexyl)isoindoline-1,3-dione is playing an increasingly important role. we look forward to future research findings about 104618-32-8.

Reference:
Patent; SmithKline Beecham P.L.C.; US5464864; (1995); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem