496-12-8, Adding some certain compound to certain chemical reactions, such as: 496-12-8, name is Isoindoline, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 496-12-8.
General procedure: Benzyl bromide 3 (1.0 eq), the appropriate nucleophile (1.2 eq), and K2CO3 (1.2 eq) were dissolved in dry DMF (3 mL) under an inert atmosphere. The reaction stirred at room temperature overnight.The reaction mixture was partitioned between 2 M NaOH and ethyl acetate. The aqueous layer was extracted with additional ethyl acetate. Combined organic layers were dried over MgSO4, filtered, and concentrated under vacuum to obtain the product.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 496-12-8.
Reference:
Article; Montgomery, Deanna; Anand, Jessica P.; Baber, Mason A.; Twarozynski, Jack J.; Hartman, Joshua G.; Delong, Lennon J.; Traynor, John R.; Mosberg, Henry I.; Molecules; vol. 24; 23; (2019);,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem