2058-74-4, Name is 1-Methylisatin, 2058-74-4, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows.
General procedure: A mixture of isatin derivative (1.0mmol), activated methylene (1.0mmol), 1,3-diketones (1.0mmol), and Fe3O4SiO2-imid-PMAn catalyst (0.8mol%) was stirred at 70C in water or irradiated in a microwave oven at 200W for an appropriate period of time as indicated in Table 2. After completion of the reaction, as indicated by TLC, the reaction mixture was diluted with hot ethanol (10mL). The catalyst was removed by using a magnetic field and then the solvent was evaporated and the pure product was obtained by recrystallization from ethanol.
Statistics shows that 1-Methylisatin is playing an increasingly important role. we look forward to future research findings about 2058-74-4.
Reference:
Article; Esmaeilpour, Mohsen; Javidi, Jaber; Divar, Masoumeh; Journal of Magnetism and Magnetic Materials; vol. 423; (2017); p. 232 – 240;,
Indoline – Wikipedia,
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