3484-35-3, Adding a certain compound to certain chemical reactions, such as: 3484-35-3, name is 5-Methylindolin-2-one, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3484-35-3.
General procedure: The reaction mixture of the substituted oxindole (1 equiv), the substituted salicylaldehyde (1.2 equiv) and piperidine (0.1 equiv) in ethanol (1-2 mL/1 mmol) was stirred at 90 C for 3-5 h. After the reaction mixture cooled down, the precipitate was filtered and washed with cold ethanol and diethyl ether, successively. Allowed to dry, the product was used in subsequent reaction without further purification.
According to the analysis of related databases, 3484-35-3, the application of this compound in the production field has become more and more popular.
Reference:
Article; Zhang, Lidan; Ren, Wen; Wang, Xiaoyan; Zhang, Jiaying; Liu, Jie; Zhao, Lifeng; Zhang, Xia; European Journal of Medicinal Chemistry; vol. 126; (2017); p. 1071 – 1082;,
Indoline – Wikipedia,
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