Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 496-12-8, name is Isoindoline, This compound has unique chemical properties. The synthetic route is as follows., 496-12-8
(Intermediate Example 115) 3-Amino-1-(1,3-dihydroisoindol-2-yl)propan-1-one N-(3-Dimethylaminopropyl)-N’-ethylcarbodiimide hydrochloride (1.94 g) was added to a solution of 3-t-butoxycarbonylaminopropionic acid (1.90 g) in N,N-dimethylformamide at 0C. A solution of 2,3-dihydro-1H-isoindole (1.00 g) in N, N-dimethylformamide was added thereto. The mixture was warmed to room temperature and stirred overnight. The reaction mixture was concentrated under reduced pressure, and water and dichloromethane were added to the residue. The organic phase was separated and washed with 10% citric acid solution, 4% sodium bicarbonate solution and a saturated saline solution. The product was dried over sodium sulfate anhydrous and concentrated under reduced pressure. Ether was added to precipitate crystals, and the crystals were collected by filtration and dried under reduced pressure to give t-butyl [3-(1,3-dihydroisoindole)-3-oxopropyl] carbamate (1.33 g, Y.: 55%) as pale orange crystals.
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Reference:
Patent; SANWA KAGAKU KENKYUSHO CO., LTD.; EP1595866; (2005); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem