The chemical industry reduces the impact on the environment during synthesis 1127-59-9, name is 7-Methylindoline-2,3-dione, I believe this compound will play a more active role in future production and life. 1127-59-9
Step 1:7-methyl-1,3-dihydro-indol-2-one5.00 g (31.0 mmol) 7-methyl-1H-indol-2,3-dione in 18.1 mL (372 mmol) hydrazine hydrate were heated to 110¡ã C. for 3 h.Then the reaction mixture was cooled, the precipitate formed was suction filtered and washed with water.The precipitate was suspended in water, acidified with conc. hydrochloric acid and stirred for 10 min.Then the reaction mixture was stirred for a further 30 min in the ice bath, the precipitate was suction filtered, washed with water and dried.Yield: 1.60 g (35percent of theoretical)ESI-MS: m/z=148 (M+H)+
The chemical industry reduces the impact on the environment during synthesis 1127-59-9. I believe this compound will play a more active role in future production and life.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; US2011/59954; (2011); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem