New downstream synthetic route of 774-47-0

The chemical industry reduces the impact on the environment during synthesis 774-47-0. I believe this compound will play a more active role in future production and life.

The chemical industry reduces the impact on the environment during synthesis 774-47-0, name is 5,6-Difluoroindoline-2,3-dione, I believe this compound will play a more active role in future production and life. 774-47-0

6-Ethylthio-5-fluoroindole-2,3-dione 6-Ethylthio-5-fluoroindole-2,3-dione was prepared from 5,6-difluoroindole-2,3-dione using sodium thioethoxide according to the method described in the synthesis of 5-fluoro-6-methylthioindole as a brown solid (2.53 g, 19%): mp 215 C.; IR numax (Nujol)/cm-1 3286, 2926, 2855, 1766, 1712, 1619, 1467 and 1038; NMR deltaH (400 MHz, DMSO-d6) 1.32 (3H, t, J 7.5 Hz), 3.13 (2H, q, J 7.5 Hz), 6.77 (1H, d, J 6.0 Hz), 7.39 (1H, d, J 8.5 Hz), 10.97 (1H, brs).

The chemical industry reduces the impact on the environment during synthesis 774-47-0. I believe this compound will play a more active role in future production and life.

Reference:
Patent; Vernalis Research Limited; US6380238; (2002); B1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem