The chemical industry reduces the impact on the environment during synthesis 104618-32-8, name is 2-(4-Oxocyclohexyl)isoindoline-1,3-dione, I believe this compound will play a more active role in future production and life. 104618-32-8
Example 1 Preparation of 2-Amino-6-phthalimido-4,5,6,7-tetrahydrobenzothiazole hydroiodide: (8) 1000 g of 4-(Phthalimido)cyclohexanone, 1150 g of Iodine, 690 g of Thiourea and 13 liters of 2-Propanol are added to the round bottom assembly at room temperature. The resulting solution is refluxed with stirring for 24 hours and then cooled to room temperature and filtered. The wet cake is stirred with 10 liters of water at room temperature for 1 hour. The solid is filtered, washed with 2 liters of water and dried in a vacuum oven for 8-10 hours at 65C to give 1.55 kg of compound (8). Yield: 92% HPLC Purity : 96-98 % Mp : 308-310C
The chemical industry reduces the impact on the environment during synthesis 104618-32-8. I believe this compound will play a more active role in future production and life.
Reference:
Patent; SANDOZ AG; EP1731514; (2006); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem