1336963-95-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1336963-95-1, name is 6-Bromo-7-fluoroindoline-2,3-dione belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below.
To a solution of 6-bromo-7-fluoroindoline-2,3-dione (1.41 g, 5.80 mmol) in 2 N NaOH (15 mL), H2O2 solution (30%, 3 mL) was added at 0oC and the resulting mixture was stirred at 0oC for 30 minutes. After stirring at room temperature for 16 hours, the mixture was poured into ice-water, and acidified with concentrated HCl. The precipitate was collected by filtration and air dried to afford compound 5-5 (1.2 g, 89% yield) as a white solid.
The synthetic route of 1336963-95-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ARAXES PHARMA LLC; LI, Liansheng; FENG, Jun; LONG, Yun, Oliver; LIU, Yuan; REN, Pingda; LIU, Yi; (135 pag.)WO2017/58915; (2017); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem